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Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences | Clinical Trials | Clareo Health

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Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences

Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences: A 6-week Randomized Controlled Trial

NCT07124533•Loma Linda University

View on ClinicalTrials.gov

Summary

Objectives: To evaluate the effectiveness of toothpaste tablets when compared to conventional dentifrices in removing plaque. Methods: 50 participants are randomized into two groups: Denttabs toothpaste tablets (T) and Colgate's Cavity Protection toothpaste (P). Both groups utilize their assigned dentifrice for 6 weeks. A pre and post-assessment measures the Gingival Index (GI) and Plaque Index (PI) and Decayed, Missing and Filled Teeth (DMFT). A questionnaire on the use of the product is distributed at the end of the study.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•1. Subjects are 18 years or older;
•2. Subjects who will comply with study protocol;
•3. Subjects who can read and understand the consent form;
•4. Subjects available during the study period;
•5. Subjects have more than 20 teeth.

Exclusion Criteria

•1\. Subjects under the age of 18.

Locations (2)

Loma Linda University Health

Loma Linda, California, United States

Loma Linda University

Loma Linda, California, United States

Key Dates

Start Date

May 1, 2026

Primary Completion Date

December 1, 2026

Completion Date

December 1, 2026

Last Updated

January 30, 2026

Enrollment

ESTIMATED participants

Conditions

Gingival InflammationDental Caries

Interventions

Toothpaste Tablet

DRUG

Conventional Toothpaste

DRUG

Contacts

So Ran Kwon, DDS, MS, PhD

CONTACT

909 558 5118 sorankwon@llu.edu

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 30, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences

Inclusion Criteria

Exclusion Criteria

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