The First Affiliated Hospital of Shanxi Medical University
The Third People's Hospital of Taiyuan
The First Affiliated Hospital of Henan University of Science and Technology
Age
18–any
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Adults aged ≥18 years old
Clinically diagnosed with liver cirrhosis
Endoscopic observation to determine the presence of esophagogastric varices
Only eligible for the portal vein pressure measurement group if there are no signs of variceal bleeding for at least 14 days
Participant or guardian is capable of comprehending the study protocol, willing to participate, and able to provide written informed consent
You may not be if
Severe congestive heart failure, or severe untreated valvular heart disease
Moderate to severe pulmonary hypertension
Uncontrolled systemic infection
Lesions (e.g., cysts) or tumors in the liver parenchyma that preclude TIPS creation
Overt hepatic encephalopathy
Unrelieved biliary obstruction
Child-Pugh score \> 13
MELD score \> 18
INR \> 5
Platelet count \< 20 ×109/mm3
No gastrointestinal bleeding (suitable for the ultrasound examination group and the endoscopic ultrasonography group)
Participants who had undergone hand or wrist surgery within the previous 3 months or were unable to hold the dynamometer with the testing hand were excluded from the study.
Clareo Health | Effect of Handgrip Strength on Portal Vein Hemodynamics in Patients With Liver Cirrhosis
