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Effectiveness of Bromelain Supplement in Reduction of Facial Swelling Caused by Orthognathic Surgery
The goal of this clinical trial is to learn if Bromelain Supplement works to decrease the amount of swelling or the amount of time swelling is present following jaw surgery. It will also learn about the safety of Bromelain supplement. The main questions it aims to answer are: Does Bromelain decrease facial swelling following orthognathic, or jaw, surgery? Does Bromelain supplement decrease the amount of time that patients are swollen following orthognathic, or jaw, surgery? Participants will: Take Bromelain supplement once daily for 9 days total. Take 2 days before surgery and 7 days following surgery. Keep a log of when the bromelain supplement is taken as well as another other medications. Visit the clinic with pre and post surgical protocol
Age
18 - 65 years
Sex
ALL
Healthy Volunteers
No
University of Kentucky
Lexington, Kentucky, United States
Start Date
September 8, 2025
Primary Completion Date
April 1, 2026
Completion Date
April 1, 2026
Last Updated
September 24, 2025
200
ESTIMATED participants
Bromelain
DIETARY_SUPPLEMENT
Lead Sponsor
Mohamed Bazina
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT04117360