Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Shirley Ryan AbilityLab
With
National Institute of Neurological Disorders and Stroke (NINDS)
Here we aim to observe effects of acute intermittent hypoxia in persons who have experienced a single stroke. We have previously shown this technique to be safe and effective at increasing strength in persons with disabilities, and here are aiming to determine the mechanism of how the breathing method modulates motor function.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
A first time, unilateral, ischemic, hemispheric stroke, confirmed by MRI
Chedoke stage of hand assessment \>= 3
Ability to open and close affected hand
Able to understand and communicate in english
Able to independently consent
over 6 months post stroke
Must have a hemoglobin level above 10g/dl
Must have ability to leave research visit with a compainon/group trasportation
WOCBP must be comfortable confirming negative pregnancy prior to hypoxia
Must not be involved in any other research intervention study testing upper extremities
You may not be if
History of prior neurological disorders
Brain stem or cerebellar stroke; mean Fazekas score rated on initial fluid-attenuated inversion recovery MRI greater than equal to 3
Severe Aphasisa
Pre-existing hypoxic pulmonary disease
Includes positive Covid-pneumonia diagnosis within 1 year of screening visit
