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RECRUITINGNA

Robot-assisted Versus Open Lateral Pancreaticojejunostomy for the Treatment of Symptomatic Chronic Pancreatitis (PANACOTTA)

Robot-assisted Versus Open Lateral Pancreaticojejunostomy for the Treatment of Symptomatic Chronic Pancreatitis (PANACOTTA): a Multicenter Randomized Controlled Trial

NCT07109180•Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

View on ClinicalTrials.gov

Summary

PANACOTTA is a multicenter randomized controlled trial including patients with symptomatic chronic pancreatitis and a dilated main pancreatic duct to either robot-assisted or open lateral pancreaticojejunostomy. The PANACOTTA trial will assess the post-operative quality of recovery following robot-assisted versus open lateral pancreaticojejunostomy.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•At least 18 years old
•Indication for (extended or partial) lateral pancreaticojejunostomy as agreed during multidisciplinary team meeting based on symptomatic chronic pancreatitis (i.e. morphine dependent pain or recurrent acute flares of pancreatitis, at least 3 episodes per year) and a dilated pancreatic duct of ≥ 5 mm, with a non-enlarged pancreatic head \< 40 mm
•Confirmed CP, according to the M-ANNHEIM diagnostic Criteria24
•Eligible for both an robot-assisted and open approach
•Obtained written informed consent

Exclusion Criteria

•Suspected or confirmed current pancreatic cancer
•ASA classification ≥ 4
•Other painful conditions aside from CP, with pain difficult to discriminate from CP pain
•Prior pancreatic surgery
•Pregnancy

Locations (1)

Amsterdam UMC

Amsterdam, Netherlands

Key Dates

Start Date

April 16, 2025

Primary Completion Date

December 31, 2026

Completion Date

December 31, 2026

Last Updated

August 7, 2025

Enrollment

ESTIMATED participants

Conditions

Chronic PancreatitisSurgeryMinimally Invasive Surgical TechniqueRobot SurgicaRobot SurgeryMinimally Invasive SurgeryPancreaticojunostomy

Interventions

Robot-assisted lateral pancreaticojejunostomy

PROCEDURE

Open lateral pancreaticojejunostomy

PROCEDURE

Contacts

E. Kilinc

CONTACT

+31652741059 e.kilinc@amsterdamumc.nl

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 7, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Robot-assisted Versus Open Lateral Pancreaticojejunostomy for the Treatment of Symptomatic Chronic Pancreatitis (PANACOTTA)

Inclusion Criteria

Exclusion Criteria

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