This research is a cross-sectional study conducted to investigate the prevalence and severity of psychological distress, including depression, anxiety, and stress, among breast cancer patients in Anbar, Iraq. The study utilized standardized and validated questionnaires (such as PHQ-9, GAD-7, and Perceived Stress Scale) to assess the mental health status of participants. Data on clinical variables, cancer stage, treatment modalities, and socio-demographic characteristics were collected to identify potential predictors of psychological distress. Statistical analyses were performed to explore associations between psychological outcomes and clinical or demographic factors. The results of this study aim to provide evidence to guide psychosocial interventions and enhance patient care strategies in oncology centers.