Age

18–any

Sex

ALL

Healthy volunteers

Not accepted

Received prior treatment with an antibody drug conjugate with a camptothecin-class payload (e.g. sacituzumab govitecan, trastuzumab deruxtecan )
Active anorexia, nausea or vomiting, and/or signs of intestinal obstruction meeting protocol exclusion
Pulmonary disease meeting protocol exclusion
Other unacceptable abnormalities as defined by protocol

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors