Established diagnosis of RA according to American College of Rheumatology/European league Against Rheumatism (ACR/EULAR) 2010 criteria (Aletaha et al., 2010), presented with moderate to high disease activity identified as disease activity score-28 based on C-reactive protein (CRP) levels (DAS-28-CRP) \>3.2.
Patients receiving stable regimen of one or more csDMARDs for at least the past 3 months.
RA Patients with Moderate or high disease activity identified as disease activity score-28 based on C-reactive protein (CRP) levels (DAS-28-CRP) \>3.2.
You may not be if
Patients receiving biologic DMARDs therapy for RA
Patients taking any other anti-inflammatory drugs
Patients taking any other antioxidants
Pregnant and lactating women
Other rheumatological, inflammatory diseases or malignancies
Smokers
Thyroid illnesses
Patients with impaired liver functions (liver transaminases level ≥ three times upper normal limits), impaired kidney functions (estimated glomerular filtration rate (eGFR) \< 30 ml/min)
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