Finding studies
Finding studies
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Lead
AstraZeneca
With
This study is an open-label, fixed-sequence, drug-drug interaction study of orally administered rosuvastatin in the presence and absence of capivasertib in healthy participants. The study will comprise: 1. A Screening Period of maximum 28 days. 2. Two Treatment Periods * Period 1: Participants will receive single oral dose of rosuvastatin. * Period 2: Participants will receive two single oral doses of capivasertib administered 12 hours apart, with the first capivasertib dose being concomitantly administered with a single oral dose of rosuvastatin. 3. A final Follow-up Visit within 7 to 10 days after the last study intervention administration. There will be a minimum washout period of at least 7 days between the first dose of rosuvastatin (in Treatment Period 1) and the second dose of rosuvastatin (in Treatment Period 2).
Age
18–60
Sex
ALL
Healthy volunteers
Accepted
