Assessment of Different Medications in Modifying the Efficacy of Anesthesia in Mandibular Molars With Acute Irreversible Pulpitis

Exclusion Criteria

• •• Individuals with significant health issues: a history of gastrointestinal disorders, active bronchial asthma, renal diseases, liver dysfunction, heart diseases, blood disorders, hypertension or poorly controlled diabetes mellitus.
• •* Immunocompromised patients.
• •* Sensitivity or allergy to any of the pharmaceuticals or medications intended for use in the study
• •* Participants who could not read, comprehend, or complete the baseline pain scale questionnaire.
• •* Cases where clinical examination suggested necrotic teeth leading to a false positive diagnosis.
• •* Teeth exhibiting periodontal disease or periapical lesions confirmed through clinical assessment and pre-operative radiographs.
• •* Sensitivity to percussion or palpation in the included teeth