Effects of Acute Sleep Deprivation on Individuals With Different APOE Genotypes

Exclusion Criteria

• •Presence of day-night sleep reversal
• •Shift work within the past 6 months
• •Travel across time zones or experience of jet lag within the past three weeks
• •Current smoking or nicotine use; alcohol consumption exceeding five standard units per week (one standard alcohol unit is defined as 10 mL \[or 8 g\] of pure alcohol)
• •Consumption of strong tea, coffee, or caffeine-containing foods and beverages within one week before study participation
• •Family history of early-onset dementia
• •Self-Rating Depression Scale (SDS) score ≥ 53, Self-Rating Anxiety Scale (SAS) score ≥ 50
• •Female participants who are currently pregnant or breastfeeding
• •Individuals who need to drive or operate vehicles or machinery during the study period