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"Association Between Isokinetic Lower Extremity Muscle Strength and Bone Mineral Density in Elderly Women With and Without Osteoporosis: A Case-Control Study" | Clinical Trials | Clareo Health

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"Association Between Isokinetic Lower Extremity Muscle Strength and Bone Mineral Density in Elderly Women With and Without Osteoporosis: A Case-Control Study"

NCT07084857•Cairo University

View on ClinicalTrials.gov

Summary

bone density and muscle strength appear to be more related to each other. Examining the association between muscle strength and bone health is very important in recognizing risk factors for lower extremity muscle weakness.

Detailed Description

Dual Energy X-ray Absorptiometry (DEXA) scan will be used to assess hip bone mineral density (BMD) at femoral head region. Isokinetic PT of hip flexors, extensors, abductors and adductors and knee flexors and extensors will be measured using Biodex System 3 Isokinetic Dynamometer. The measured outcomes will be evaluated at an angular velocity of 60°/sec in a concentric mode of muscle contraction for five successive repetitions. Isokinetic testing will be done at the Isokinetic Laboratory, Faculty of Physical therapy, Cairo University.

Eligibility

Age

50 - 70 years

Sex

FEMALE

Healthy Volunteers

Inclusion Criteria

•1. The group of OP (n=33) has femoral BMD T-scores below -2.5 diagnosed by DEXA scan according to the WHO \[8\] classification of BMD in 2003,
•2. The control group has normal BMD T-scores more than -1.

Exclusion Criteria

•1. There was any neurological, musculoskeletal, rheumatologic, respiratory or cardiovascular problem.
•2. They were receiving medications that result in bone loss such as corticosteroids,
•3. They had vertigo, dizziness, or any vestibular problem,
•4. They had hyperthyroidism or hyperparathyroidism. 6- They actively participate in sports activities,
•5. They underwent previous surgery (e.g; joint replacement) or history of fractures of the lower extremity.

Locations (1)

Azza Mohammed

Giza, Egypt

Key Dates

Start Date

February 8, 2025

Primary Completion Date

March 28, 2025

Completion Date

March 29, 2025

Last Updated

July 25, 2025

Enrollment

ACTUAL participants

Conditions

Osteoporosis

Interventions

correlational analysis between BMD and isokinetic lower extremity strength

OTHER

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RECRUITING

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 25, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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"Association Between Isokinetic Lower Extremity Muscle Strength and Bone Mineral Density in Elderly Women With and Without Osteoporosis: A Case-Control Study"

Inclusion Criteria

Exclusion Criteria

OsteoPorotic fracTure preventION System (OPTIONS) Research Study

Smart Wearable Device (gaitQ): Walk Better Project

Step-down Therapy After Long-term Osteoporosis Treatment

Automated Bone Age Estimation From Noncontrast Abdominal CT Using Deep Learning

Effect of Mechanical Loading and Bone Loss on Motor Neuron Activity-H-Reflex Relationship

Clinical Study to Estimate Bone Mineral Density With the POROUS Ultrasound Device