External Carotid Blood Flow in Individuals With Post-Bariatric Hypoglycemia

Visit 1 (Screening) This visit will last about 2 hours. Participants will be asked to come to Joslin Diabetes Center. During the screening visit, a study team member will go over the informed consent form with participants and will explain why this study is being done and the study procedures involved. Participants will have to sign the consent form before any study related procedures take place. After participants sign the consent, the following procedures will be done to ensure eligibility and that it is safe to be part of the study. * Review medical history by the study doctor. * Participants will be asked to sign a release of information form so that the investigators may obtain additional information about medical history from prior physicians and hospitals. Medical records including laboratory results (within the last 6 months) will be reviewed by the study doctor. * Physical examination, vital signs and anthropometrics (blood pressure, heart rate, temperature, height and weight) and an otoscopic exam (a look inside the external ear). * Urine pregnancy test (if participant is a female of child bearing potential) that must be negative in order to continue participation. * Questionnaires: Investigators will ask participants to fill out several questionnaires that will help the investigators assess any symptoms of low blood sugar or autonomic symptoms: * Edinburgh Hypoglycemia Symptom Scale (EHSS) * Dumping Symptom Rating Scale (DSRS) questionnaire * Composite Autonomic Symptom Score (COMPASS 31) * Orthostatic Hypotension Questionnaire (OHQ) * Devices: If the participant is eligible, a member of the study team will place the following devices. The participant will wear both devices for 10 days (24 hours per day) · Lumia Health: A small in-ear wearable device will be placed to monitor the blood flow to the head. The study team will make sure it fits comfortably and show the participant how to use it properly. A member of the Lumia team may be present during the placement of the device in order to assist the study team with choosing the best size of the device to match the shape of the participant's ear. If the participant is uncomfortable with this, study team members will be able to perform this procedure (after receiving instructions from a Lumia team member). Procedure: (1) Removing earrings or jewelry if needed and cleaning the outer ear to ensure a secure fit. (2) Positioning the device on the frontal surface of the left ear cartilage. (3) Adjusting it to fit comfortably. If participant experiences any discomfort during placement, they will be asked to inform the study team. Employees at Lumia Health will process signals from the device and provide the Joslin team with the blood flow information. This information will be de-identified, meaning it will not include any personally identifiable data. Dexcom G6 Pro: This continuous glucose monitor (CGM) will be placed under the skin on the abdomen to monitor the participant's sensor glucose (sugar) levels. Insertion Procedure: (1) A suitable location on the abdomen is identified. (2) The CGM is placed against the skin at the chosen site. The sensor is inserted in the skin with a simple press or click; this causes little to no discomfort. (3) A small transmitter is connected to the sensor to allow glucose readings to be transmitted to a monitoring device (receiver), which the participant will keep with them during the duration of the monitoring period. Diaries: Investigators will ask participants to keep a written paper diary of daily meals, liquids (including caffeinated beverages), physical activity and any issues with the device (Lumia). At the end of the visit, the participant will be scheduled for the next 2 visits. Additionally, the participant will be provided contact information for the study team in case any questions or issues arise during the study. Visit 2 (Follow up) This visit will happen remotely, between days 4-6 after Visit 1. A study team member will call the participant by video or phone. This visit will include: Wellness check: The investigators will check how the participant is doing, see if there are any problems, and ask about experience with both the ear and CGM devices. Ear device check: A member of the study team will review the data collected on the cloud from previous days to ensure the ear device is functioning properly. If everything is working well, the investigators will encourage participants to continue wearing the device . If there are issues with data collection or problems with device, the investigators will provide instructions to improve data collection and schedule a follow-up call if needed. Questions and support: Investigators will be available to answer any questions that the participant may have. At the end of this call visit, the investigators will provide instructions for the next visit. Visit 3 (End of Study) This visit will last approximately 2 hours at the Joslin Diabetes Center. The visit will include the following: Review medical history, including any updates since the last visit. Physical examination, vital signs (blood pressure, heart rate, temperature, height and weight) and an otoscopic exam (a look inside the external ear). Review of diaries the participant completed during the study. The participant will be asked to complete the same surveys as at Visit 1 and additional surveys about the experience with the device. The participant will return study devices to the study team so the information can be downloaded for analysis. The investigator will review the glucose monitoring information with the participant at the end of this visit, but will not be able to review data from the ear device.