Adults (aged over 18years) who are healthy but overweight/obese (BMI 27-45kg/m2) males and females as:
15 women (age 40 or less years)
15 men (age 40 or less years)
15 women (age 55-65 years) in menopause\*; not taking Hormone Replacement Therapy (HRT)
15 men (age 55-65 years)
15 women (age 55-65 years) in menopause; taking HRT\*\*
You may not be if
Potential volunteers will be asked to fill in a health questionnaire at the screening visit to assess their suitability for the study. This information will allow us to exclude participants.
Females who are planning to be pregnant, are pregnant or are breastfeeding
Anyone with coeliac disease or gluten intolerance or food allergy
Anyone with diagnosed T1 or T2 diabetes
Anyone suffering from a psychiatric disorder or any type of substance abuse
Anyone following a vegetarian or vegan diet
Anyone currently following a weight loss programme (that may be affecting lifestyle, physical activity \& diet) or undergone gastric band/reduction surgery; including GLP agonist (e.g. Semaglutide injection, Ozempic®).
Anyone currently participating in another research study
Anyone with unsuitable veins for blood sampling
Anyone who is unable to fluently speak, read and understand English
Anyone who is unable to comply to an alcohol-free diet for 6 weeks
Anyone unable to give fully informed consent
Clareo Health | Sex Hormones as Regulators of the Age- and Sex-dependent Benefits of Caloric Restriction
