Patients who self-identify as 'exercisers' e.g. routinely exercise for minimum of 45 min/day, 5x/week

Pregnant (unable to conduct bone density measurements in pregnant females)

Hypogonadal, must be on replacement sex hormone therapy for min of 6 months

Cardiac T2\* by Magnetic Resonance Imaging of \<20 ms (e.g. evidence of cardiac iron overload)

Recent long bone or vertebral fracture (within the last 6 months)

Cognitive impairment limiting ability to understand instructions during orientation

Other conditions known to influence bone health or body composition as determined by the investigator

Patients at risk for cardiovascular disease yet have not received a routine cardiology assessment within the previous 12 months

Bone medication (e.g. Zometa, Prolia, Forteo) use in previous 2 years

Effect of Exercise on Body Composition and Bone Health in Patients With Thalassemia