National Institute of General Medical Sciences (NIGMS)
Age
18–65
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
18 and 65 years of age
free of any significant underlying medical problems based upon a detailed medical history and physical exam, and normal resting electrocardiogram.
You may not be if
Known heart disease
other chronic medical conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, and uncontrolled hypertension, etc. as well as serious abnormalities detected on routine screening.
Individuals who are pregnant, planning to become pregnant, or breastfeeding will be excluded, this will be confirmed in females using a urine pregnancy test.
Taking prescribed medications (such as beta blockers and non-dihydropyridine calcium channel blockers) or over-the-counter medications that have known influences on thermoregulatory response.
Current smokers, as well as individuals who regularly smoked within the past 3 years.
body mass index is ≥ 31 kg/m2.
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