Diagnosis of HS for at least 6 months before screening visit.
Diagnosis of HS (Hurley Stage I, II, III) with a total abscess and inflammatory nodule count of at least 4 and affecting at least 3 distinct anatomical areas at screening and Day 1 visits.
Total estimated treatment BSA \> 20% at screening and baseline.
Agreement to not use topical or systemic antibiotics for treatment of HS during the Maximal Use Treatment Period.
Willingness to avoid pregnancy or fathering children based on the criteria defined in the protocol.
You may not be if
Current or history of skin condition(s) other than HS that might confound the evaluation of HS; clinically uncontrolled cardiovascular disease; thrombosis; certain cancers; certain infections; severe anemia, thrombocytopenia, or neutropenia; other medical conditions at the discretion of the investigator.
Laboratory values outside of the protocol-defined ranges.