Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Ioannina
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adults aged ≥18 years with stable CKD, defined as:
eGFR \< 60 mL/min/1.73 m², or
eGFR ≥ 60 mL/min/1.73 m² with documented evidence of kidney damage (persistent albuminuria, structural abnormalities on imaging or histology, or genetic kidney disease).
You may not be if
Any signs of dermal infections, open wounds, or skin irritation.
Significant variations in eGFR in the last two months, defined as any absolute change (either increase or decline) in eGFR of \>10 mL/min/1.73m2 ;
Patients with a functioning kidney graft;
Patients receiving immunosuppression treatment;
Patients with kidney stones;
Patients with uncontrolled hypertension (a systolic blood pressure (SBP) \>150 mmHg and/or diastolic blood pressure (DBP) \>90 mmHg with measurements taken under standardized conditions (e.g after a 5-minute seated rest, using validated equipment);
Patients receiving drugs reported to affect serum levels of creatinine and cystatin-c without affecting kidney function (i.e. cimetidine, trimethoprim, and fibrates);
Known allergy to pilocarpine,
Glaucoma;
Patients with metal implants;
Pregnancy;
Active malignancy;
Low life expectancy (\<6 months) according to investigators judgement
