MeDex: No Perioperative Dexamethasone in Brain Metastases

Inclusion Criteria

• •1. New brain tumor(s) on imaging
• •2. Visceral mass(es) suspicious or confirmed for neoplasm
• •a. Patients with lung mass suspicious for primary lung cancer and no prior diagnosis must undergo biopsy of the lung mass prior to resection of brain metastasis(es) to exclude histology (i.e., small cell lung carcinoma) that would not benefit from resection
• •3. No contraindications for craniotomy
• •4. Age ≥ 18 years
• •5. ECOG performance status ≤ 2 (i.e., ambulatory \> 50% of waking hours)
• •6. Midline shift on MRI ≤ 10 mm
• •7. Craniotomy planned to resect \>75% of the enhancing mass (surgeon's judgment)