W8M-MC-GN02:

Individuals who are of childbearing potential

Have a history of acute or chronic pancreatitis

Have any of the following cardiovascular conditions within 6 months prior to screening:

* acute myocardial infarction

* cerebrovascular accident (stroke)

* unstable angina, or

* hospitalization due to congestive heart failure.

W8M-MC-CWMM:

Have a prior or planned surgical treatment for obesity, except prior liposuction or abdominoplasty, if performed \>1 year prior to screening

Have type 1 diabetes mellitus, latent autoimmune diabetes in adults, or history of ketoacidosis or hyperosmolar coma

Have poorly controlled hypertension

Have signs and symptoms of any liver disease other than nonalcoholic fatty liver disease

Have a history of symptomatic gallbladder disease within the past 2 years

Have a lifetime history of suicide attempts

A Study of LY3549492 in Adults With Obesity or Overweight With Type 2 Diabetes