Has a clinical diagnosis of HCM consistent with current American College of Cardiology/American Heart Association and European Society of Cardiology Guideline definitions
Has had confirmation of nHCM by the echocardiography core laboratory based on screening rest and exercise stress echocardiography
New York Heart Association (NYHA) functional Class II or III at screening
Functional limitation as defined by a screening CPET
You may not be if
Has a known or suspected infiltrative, genetic, or storage disorder causing cardiac hypertrophy that mimics nHCM
Has any other condition judged by the investigator to be the primary cause of dyspnea, exercise intolerance, and/or angina
Has an inability to exercise on a treadmill or bicycle (eg, orthopedic limitations)
Has any medical condition that precludes upright exercise stress testing
Clareo Health | A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
