Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Shanghai Gynecologic Oncology Group
Age
35–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Patients meeting either of the following criteria based on initial diagnostic pelvic ultrasound findings (pelvic mass or pelvic effusion) suspicious for ovarian malignancy or at elevated risk for ovarian cancer:
1. Postmenopausal women or females ≥45 years with pelvic mass or effusion on ultrasound;
2. Postmenopausal women or females ≥45 years with serum CA125 ≥35 U/mL;
3. Females ≥35 years with a confirmed family history of ovarian or breast carcinoma;
4. Females ≥35 years harboring pathogenic/likely pathogenic BRCA1/2 germline mutations;
5. Females ≥35 years with BRCA1/2 mutations, non-suspicious adnexal lesions on ultrasound but planning prophylactic adnexectomy with availability of serial pathological sectioning.
② Ability to comply with the study protocol and adhere to scheduled follow-up assessments.
③ Provision of written informed consent.
You may not be if
* ① Pregnant individuals
* Patients with histopathologically confirmed ovarian cancer
* Ovarian malignancy diagnosed by PET-CT at this institution
④ Patients undergoing neoadjuvant chemotherapy for confirmed ovarian cancer
⑤ Claustrophobia precluding tolerance of MRI examination
⑥ Contraindications to MRI: cardiac pacemakers, ferromagnetic implants, or high-risk metallic foreign bodies
⑦ History of gadolinium-based contrast agent (GBCA) hypersensitivity or intolerance
⑧ Severe renal insufficiency (glomerular filtration rate \<30 mL/min/1.73 m²)
Clareo Health | O-RADS MRI System on Early Detection of Ovarian Cancer
