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A Long-term Extension Study to Evaluate the Safety and Efficacy of APG777 in Patients With Atopic Dermatitis Previously Treated With APG777
This is a multicenter, double-blind, Long-Term Extension (LTE) study to evaluate the long-term safety and efficacy of APG777 in patients with moderate-to-severe AD who have completed treatment in an APG777 Parent Study (NCT06395948). The LTE study will consist of 3 periods: 1) Screening Visit will coincide with the last visit of the Maintenance Period in the Parent Study 2) Extended Treatment Period 3) Post-treatment Follow-up Period. This study will be conducted in participants with atopic dermatitis (AD) who completed the Treatment Period in a prior APG777 study and who, in the opinion of the Investigator, would benefit from long-term treatment with APG777.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Investigational Site
Fountain Valley, California, United States
Investigational Site
Los Angeles, California, United States
Investigational Site
Coral Gables, Florida, United States
Investigational Site
Jacksonville, Florida, United States
Investigational Site
Margate, Florida, United States
Investigational Site
Douglasville, Georgia, United States
Investigational Site
Skokie, Illinois, United States
Investigational Site
Bowling Green, Kentucky, United States
Investigational Site
Detroit, Michigan, United States
Investigational Site
Troy, Michigan, United States
Start Date
May 14, 2025
Primary Completion Date
December 1, 2029
Completion Date
December 1, 2029
Last Updated
March 12, 2026
350
ESTIMATED participants
APG777
DRUG
APG777
DRUG
APG777
DRUG
Lead Sponsor
Apogee Therapeutics, Inc.
NCT07262983
NCT06389136
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT06342713