RENEW-AI: Personalizing Scleroderma Management With an AI Health Coach

Exclusion Criteria

• •Individuals who did not participate in the original RENEW trial
• •Individuals who lack access to reliable high-speed internet will be excluded to ensure they can fully engage with the AI-supported health coaching and digital components of the study
• •Non-English speakers will be excluded because the current version of the AI tool is available only in English
• •Individuals planning to initiate any new treatments specifically targeting fatigue, pain, or mood symptoms (such as psychological therapy, structured rehabilitation, or new medications) during the 4-week study period will be excluded, to avoid confounding effects on the study outcomes.
• •Individuals with other significant medical or logistical issues that would impede meaningful participation, such as severe concurrent medical conditions, inability to access the RENEW intervention, or cognitive impairments that prevent them from engaging with study procedures, will also be excluded.