Loading clinical trials...

SMART-CPT for PTSD/Concussion Implementation | Clinical Trials | Clareo Health

ENROLLING_BY_INVITATIONNA

SMART-CPT for PTSD/Concussion Implementation

SMART-CPT for PTSD and History of Concussion: A Pragmatic Implementation Trial

NCT06995612•San Diego Veterans Healthcare System

Summary

The clinical implementation trial will evaluate effectiveness and feasibility, acceptability, appropriateness, barriers, and facilitators of implementing SMART-CPT, a treatment targeting the two primary factors leading to poor outcomes following concussion, in Veterans. It will test effectiveness and broad implementation feasibility of SMART-CPT compared to standard Cognitive Processing Therapy (CPT).

Eligibility

Age

18 - 55 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•PTSD diagnosis;
•mild TBI sustained greater than three months prior to enrollment;
•cognitive complaints;
•not medicated or stable on prescribed psychiatric medication for at least 6 weeks prior to study enrollment with no anticipated/pending medication changes;
•English literacy.

Exclusion Criteria

•mTBI sustained less than 3 months previously;
•history of moderate, severe, or penetrating TBI;
•history of other significant neurological condition unrelated to TBI;
•severe psychiatric disturbance expected to interfere with successful completion of the study;
•current severe alcohol or other substance use disorder;
•suicidal intent or attempt within the previous month;
•current homicidal ideation;
•impaired decision making capacity;
•prior completion of five or more sessions of CPT or cognitive rehabilitation; -concurrent participation in other intervention studies for PTSD or TBI;
•life threatening or unstable medical illness;
+2 more criteria

Locations (1)

VA San Diego

San Diego, California, United States

Key Dates

Start Date

December 1, 2024

Primary Completion Date

June 1, 2027

Completion Date

June 1, 2027

Last Updated

June 4, 2025

Enrollment

124

ESTIMATED participants

Conditions

PTSDConcussion, Mild

Interventions

SMART-CPT

BEHAVIORAL

CPT

BEHAVIORAL

Testing an Integrated PTSD and Weight Management Intervention: A Hybrid Type 1 Trial

NCT07010757

PTSDObesity

View study

RECRUITINGNA

Digital Biofeedback for Combat Veterans Diagnosed With PTSD

NCT07462312

PTSD - Post Traumatic Stress Disorder

View study

RECRUITINGNA

EMDR Integrative Group Protocol and Individual Treatment for Patients With Cancer: A Pilot Study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 4, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

SMART-CPT for PTSD/Concussion Implementation

Inclusion Criteria

Exclusion Criteria

Testing an Integrated PTSD and Weight Management Intervention: A Hybrid Type 1 Trial

Digital Biofeedback for Combat Veterans Diagnosed With PTSD

EMDR Integrative Group Protocol and Individual Treatment for Patients With Cancer: A Pilot Study

Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD

Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their Children

PTSD Treatment for Incarcerated Men and Women: AV