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The Proposed Study Aims to Investigate the Efficacy of Quercetin as an Adjunctive to Mechanical Debridement in Treatment of Periodontitis | Clinical Trials | Clareo Health

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The Proposed Study Aims to Investigate the Efficacy of Quercetin as an Adjunctive to Mechanical Debridement in Treatment of Periodontitis

Efficacy of Quercetin Loaded on Chitosan Nanoparticles Gel as an Adjunctive to Mechanical Debridement in Treatment of Periodontitis: Randomized Controlled Clinical Trial

NCT06982248•Mansoura University

View on ClinicalTrials.gov

Summary

the proposed study aims to investigate the effect of Quercetin in treatment of periodontitis patients

Detailed Description

the proposed study aims to investigate the effect of Quercetin in treatment of periodontitis patients not having systemic diseases.the 2ry aim of study to estimate the neacular factor kabba B level in gingival crevicular fluids.

Eligibility

Age

25 - 55 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•\- Patients of both sexes with an age ranging between 25 and 55 years will be included in the study. Patients diagnosed as having periodontitis based on clinical and radiographic examinations will be included

Exclusion Criteria

•Insulin dependent diabetes
•Thyroid disease
•Patients with sensitivity to the medication used in the study
•patients with a history of antibiotic use or anti-inflammatory drugs during the previous 3 months prior to the study will be excluded from the study.
•Additionally, patients with systemic diseases, smokers, pregnant and lactating patients, and patients not compliant with oral hygiene procedures will also be excluded

Locations (1)

Faculty of Dentistry, Mansoura University

Aga, Egypt

Key Dates

Start Date

August 15, 2024

Primary Completion Date

February 1, 2025

Completion Date

June 1, 2025

Last Updated

May 21, 2025

Enrollment

ESTIMATED participants

Conditions

Periodontal Pocket

Interventions

NSP and chitosan nanoparticles gel loaded by quercetin

DRUG

NSP and chitosan nanoparticles gel

DRUG

scaling and root planning

PROCEDURE

Periodontal Granulation Tissue Preservation in Surgical Periodontitis Treatment

NCT05533528

Periodontal PocketPeriodontal Diseases+1 more

View study

RECRUITINGNA

Evaluation Of Nonsurgical Treatment Of Deep Periodontal Pockets (7-10mm) Using AIRFLOW® Prophylaxis Master Device With Erythritol Powder vs Conventional Instrumentation

NCT06490679

Periodontal PocketPeriodontitis+2 more

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 21, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

The Proposed Study Aims to Investigate the Efficacy of Quercetin as an Adjunctive to Mechanical Debridement in Treatment of Periodontitis

Inclusion Criteria

Exclusion Criteria

Periodontal Granulation Tissue Preservation in Surgical Periodontitis Treatment

Evaluation Of Nonsurgical Treatment Of Deep Periodontal Pockets (7-10mm) Using AIRFLOW® Prophylaxis Master Device With Erythritol Powder vs Conventional Instrumentation

Treatment Of Shallow Periodontal Pockets 4-6mm Using AIRFLOW Prophylaxis Master Device With Erythritol vs Manual Scalers

Periodontal Dressings in Non-Surgical Therapy

The Efficacy of Salvia Officinalis Gel in the Treatment of Periodontitis CLINICAL TRIAL

Comparing Photodisinfection of Chitosan NP Enriched ICG Over ICG as Adjunct to OFD: RCT