Aline JOULIE, PHD

CONTACT

Lead Sponsor

Fondation Lenval

Age

6 - 17 years

Sex

ALL

Healthy Volunteers

No

•Children aged 6 to 17 years inclusive, under 18 years old, weighing more than 10kg, and requiring analgesia for the management of acute pain
•Presenting with pain assessed as severe using a validated pain scale (VAS \> 6/10)
•Acute traumatic lime injury
•Pain caused by trauma, excluding thoracic trauma with dyspnea and abdominal pain
•Obtaining written and signe informed consent from one of the two parents or legal guardians
•Affiliation with a social security system
•Hemodynamically stable
•For post-menarche girls: negative urine pregnancy test and effective contraception, in accordance with national regulations

•Patient in a state of immediate life-threatening distress
•Parents who don't understand and/or don't speak French
•Known hypersensitivity to opiods
•Allergy to one of the study treatments
•History of epilepsy or known psychiatric illness
•History of respiratory, cardiac or renal insufficiency
•Use of serotonergic antidepressants
•Any child with an ongoing respiratory condition (asthma, laryngitis)
•Thoracic trauma
•Use of opioids within the 4 hours prior to arrival in the ermergency department
•Any child with an ongoing respiratory condition (asthma, laryngitis)
•Thoracic trauma
•Use of opioids within the 4 hours prior to arrival in the ermergency department
•History of head, abdominal, or spinal trauma
•Confirmed pregnancy
•History of toxic substance use
•Facial or nasal trauma
•Whithdrawal of informed consent from the parents or legal guardian