1\. Patients with one of the following cancer types: urothelial carcinoma, renal carcinoma, prostate adenocarcinoma, upper aerodigestive tract carcinoma, cervival carcinoma, adenocarcinoma of endometrium, cutaneous melanoma, soft tissue sarcoma, seminomatous and nonseminomatous germ cell tumors
2\. Metastatic disease for which the treatment (whatever the line) has not been initiated yet
3\. Age ≥ 18 years
4\. Patient affiliated to a French Social Security scheme
5\. Patient having signed his/her informed consent prior to inclusion in the study and prior to any specific procedure for the study.
You may not be if
1\. Patient with localized disease.
2\. Pregnant or breast-feeding women.
3\. Any psychological, family, geographical or sociological condition that prevents compliance with the medical monitoring and/or procedures set out in the study protocol.
4\. Patient who has forfeited his/her freedom by administrative or legal award or who is under legal protection (curatorship and guardianship, protection of justice).