Diagnosis of relapsing-remitting multiple sclerosis (RRMS), or primary progressive (PPMS) or secondary progressive (SPMS), defined by at least 3-6 months.
Age between 18 and 65 years.
Expanded Disability Status Scale (EDSS) between 3 and 5 to include patients with overall neurological disability from mild to moderate.
Presence of one or more of the following cognitive disorders (reported by the patient and subsequently confirmed through the Oxford Cognitive Screen-OCS):
Memory disorders
Attention disorders
Executive function disorders
Availability of internet at the patient's home necessary for the tele-rehabilitation procedures.
Adequate visual and auditory abilities to use the rehabilitation device.