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Acute Effects of Intermittent vs. Continuous Running Exercise on Physiological and Metabolic Responses
The purpose of this study is to investigate the suitability of intermittent exercise of long and short intervals at lower intensities than HIIE on energy expenditure during and post-exercise compared to MICE, as well as determine whether similar or greater effects can be achieved for glycemic control in recreationally active adults.
The same procedure will be repeated for all trials: Participants will be asked to perform 3 trials in a randomized-crossover design \[moderate-intensity continuous running (MICE: 60% V̇O2max), 5-minute interval running (5MIN; 50% and 70% V̇O2max), 2-minute interval running (2MIN; 50% and 70% V̇O2max)\]. All trials will be separated by at least 4 days wash-out and less than 14 days between trials to ensure complete rest. Sensors for measuring muscle oxygen (10 cm proximal to the mid-patella, and 2 cm lateral) will be placed on the rectus femoris muscle and 15 min resting metabolic rate was measured. After baseline measurements, participants warm-up for 3 minutes with fixed walking intensity (i.e., 5 km/h) followed by 40 minutes running. Immediately after the running, participants return to a seated position for 30 minutes post-exercise measurements (EPOC). During the EPOC and resting metabolic rate (RMR) measurement participants will sit in a comfortable position and need to limit fidgeting, thus allowed only to watch TV or videos on their phone. Participants will be wheeled to the bathroom if needed.
Age
20 - 45 years
Sex
MALE
Healthy Volunteers
Yes
National Taiwan Normal University
Taipei, Taiwan
Start Date
June 21, 2025
Primary Completion Date
April 30, 2026
Completion Date
April 30, 2026
Last Updated
January 26, 2026
16
ESTIMATED participants
Moderate-intensity continuous running (MICE: 60% V̇O2max)
BEHAVIORAL
5-minute interval running (5MIN)
BEHAVIORAL
2-minute interval running (2MIN)
BEHAVIORAL
Lead Sponsor
National Taiwan Normal University
Data Source & Attribution
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