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Combining Electrical Impedance Tomography and Thoracic Ultrasound to Investigate Dynamic Changes of Respiratory Effort, and Regional & End-expiratory Lung Volume in Mechanically Ventilated Patients.
1. To evaluate the dynamic changes of lung ultrasound during electrical impedance tomography (EIT) PEEP titration and across the first week of ARDS. 2. To asses respiratory effort by diaphragmatic function, esophageal pressure, and EIT (Pendelluft phenomenon), and hyperinflammatory biomarkers, to predict P-SILI. 3. To develop predictive models for weaning success based on integrated EELI and thoracic ultrasound.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Start Date
May 19, 2025
Primary Completion Date
December 31, 2028
Completion Date
December 31, 2028
Last Updated
May 6, 2025
50
ESTIMATED participants
Electrical impedance tomography
DIAGNOSTIC_TEST
Lead Sponsor
National Taiwan University Hospital
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT04466098