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In intensive care units, sepsis, which can be defined as bacteremia and the irregular and uncontrolled inflammatory response to it, is one of the most important causes of mortality. Early recognition of sepsis and appropriate antibiotic use for the causative agent is one of the most important steps in the fight against sepsis. Procalcitonin (PCT) is a calcitonin precursor peptide and has been reported to predict bacteremia early. While the PCT concentration level is negligible in healthy individuals, it has been shown to increase especially in bacterial infections, sepsis, trauma and burns. In our study, our aim is to determine whether there is a relationship between serum PCT concentration levels taken within 24 hours according to the time of the sample taken for blood culture with growth in patients followed up in our Internal Intensive Care Unit.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Gulhane Training and Research Hospital
Ankara, Türkiye, Turkey (Türkiye)
Start Date
March 15, 2023
Primary Completion Date
January 1, 2025
Completion Date
October 19, 2025
Last Updated
December 11, 2025
1,529
ACTUAL participants
Lead Sponsor
Gulhane Training and Research Hospital
NCT06650501
NCT04850456
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