Development and Validation of Microbiota and Metabolite-based Prediction Model for Recurrence of High-risk Colorectal Polyps After Polypectomy

Exclusion Criteria

• •patient with severe physical diseases that prevented them from adhering to the examination requirements,
• •patient with coagulopathy or other contraindications for biopsy or polypectomy,
• •patient with previous surgical procedures on the gastrointestinal tract,
• •presence of colorectal cancer or other malignant tumor at baseline
• •presence of inflammatory bowel disease or hereditary polyposis syndromes (such as family adenomatous polyposis or Lynch syndrome)
• •within 1 month before enrollment, oral antibiotics and probiotics were taken;
• •inability to provide informed consent or refusal to participate in the study.