Clinical Study of rhTPO in Hematopoietic Stem Cell Mobilization for Autologous Transplantation in Acute Leukemia

Exclusion Criteria

• •1. Liver dysfunction (alanine aminotransferase or bilirubin greater than two times the normal upper limit).
• •2. Renal dysfunction (creatinine or urea higher than 1.5 times the normal upper limit).
• •3. Any disease that could put patients at high risk, including but not limited to unstable cardiac disease, uncontrolled atrial fibrillation or hypertension, severe diabetic retinopathy
• •4. rhTPO aller- gies.
• •5. Severe prior thrombosis-event.
• •6. History of other malignancy, unless cured for more than 3 years
• •7. Pregnant or lactating women
• •8. Severe infectious disease (uncured tuberculosis, pulmonary aspergillosis)
• •9. Epilepsia, dementia or any mental disease requiring treatment.
• •10. Other conditions deemed inappropriate for study participation by the investigator.