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The goal of this study is to explore whether mitochondrial dysfunction exists in patients with chronic insomnia disorder. The main questions it aims to answer are : * Do serum mitochondrial markers change in patients with chronic insomnia? * Is there a relationship between serum mitochondrial markers and sleep and cognition in patients with chronic insomnia disorder? The researchers will compare serum mitochondrial marker levels among participants in the chronic insomnia group with those in the healthy group, and analyze the relationship between the markers and sleep and cognition of the participants. Participants will: * Complete polysomnography, the Pittsburgh Sleep Quality Index (PSQI), the Chinese-BeiJing version of the Montreal cognitive assessment (MoCA-C), the Blue Velvet Arena Test (BVAT), the Nine Box Maze Test (NBMT) to assess sleep and cognition. * The venous blood was drawn to detect mitochondrial marker levels.
Age
18 - 60 years
Sex
ALL
Healthy Volunteers
Yes
The Affiliated Chaohu Hospital of Anhui Medical University
Hefei, Anhui, China
Start Date
January 1, 2022
Primary Completion Date
January 31, 2024
Completion Date
January 31, 2024
Last Updated
May 2, 2025
120
ACTUAL participants
Lead Sponsor
Chaohu Hospital of Anhui Medical University
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