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Biventricular Remodeling in Transcatheter Tricuspid Valve Replacement
TTVR-AHI is a multicenter, retrospective registry including heart failure patients displaying a severe and symptomatic tricuspid regurgitation (TR), deemed non-eligible to cardiac surgery and therefore treated with transcatheter tricuspid valve replacement (TTVR) devices. This substudy of the main registry will focus on those with post-procedural acute hemodynamic instability (AHI).
TTVR-AHI is an international, multicenter, retrospective registry collecting routine clinical and echocardiographic data, on top of a dedicated analysis of the preprocedural CT-scan using Laralab® software. Patients with AHI will be compared to a control group without AHI, composed of individuals implanted with TTVR at Columbia University Irving Medical Center. In this substudy at Columbia, the investigators aim to describe AHI incidence, its clinical presentation, its impact on prognosis, and the predictors of its occurrence.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Columbia University Medical Center
New York, New York, United States
Start Date
January 1, 2027
Primary Completion Date
May 1, 2029
Completion Date
May 1, 2029
Last Updated
February 12, 2026
140
ESTIMATED participants
Lead Sponsor
Columbia University
NCT07191730
NCT07484009
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