Primary diagnosis of prostate cancer selected for surgical intervention (radical prostatectomy)
Primary diagnosis of organ confined (i.e. localized) untreated prostate cancer
Planned elective radical prostatectomy with bilateral nerve sparing technique
Patient has no erectile dysfunction (SHIM score ≥ 19) at the time of consultation
Willing to comply with instruction of the investigator
Willing to comply with follow-up surveys
Ability to provide written consent
Negative urinary tract infection at the time of consultation
Interest in penetrative sexual intercourse
You may not be if
High-risk cancer planned for neoadjuvant therapy, full or partial excision of neurovascular bundles
Unable to comply with learning and documenting penile rehabilitation, including oral 5-phosphodiesterase inhibitor use, vacuum pump therapy use, and/or injectable medications
History of \>14 days treatment with immunosuppressants (including systemic corticosteroids), cytotoxic chemotherapy within one month prior to initial screening, or who receive such medications during the screening period
Prior hormonal therapy such as Lupron or oral anti-androgens
Poor urinary control at baseline requiring the use of pads for leakage
Previous history of pelvic radiation
Previous history of simple prostatectomy or transurethral prostate surgery
Patients with obesity defined as body mass index (BMI) \> 40 kg/m\^2
History of open pelvic surgery ≤ 5 prior to registration (except for hernia repair)
Scheduled to undergo chemotherapy, radiation, hormone therapy, or open surgery during the study period
Any neurologic disorder or psychiatric disorder that might confound postsurgical assessments
Has any condition(s) which seriously compromises the subject's ability to participate in this study, sign consent, or has a known history of poor adherence with medical treatment
In the opinion of the principal investigator (PI), has a history of drug or alcohol abuse ≤ 12 months prior to registration
Allergic to aminoglycoside antibiotics (such as gentamicin and/or streptomycin)
Received administration of an investigational drug within 30 days prior to registration, and/or has planned administration of another investigational product or procedure during participation in this study
Clareo Health | Feasibility and Effect of Wrapping Nerves With a Multi-Layer Perinatal Tissue Allograft During Prostatectomy