Effects of Environmental Heat Exposure on Human Multiple Organ Function

Exclusion Criteria

• •1. Medications or dietary supplements intake that may alter body temperature during the study period;
• •2. Individuals who have unspecified illnesses, which in the judgment of the investigators might increase the risk associated with heat exposure will be a basis for exclusion;
• •3. Subjects with anemia, needle fainting and other signs unsuitable for blood drawing；
• •4. Subjects with cardiovascular diseases or other chronic medical condition, such as congenital heart disease, pulmonary heart disease, and hypertension, etc;
• •5. Subjects with a history of major cardio-vascular, respiratory, or nervous system surgery, etc;
• •6. Subjects with neurologic disorders, such as stroke, traumatic brain injury, epilepsy, and depression;
• •7. Subjects with allergic diseases, such as allergic rhinitis and allergic asthma, etc;
• •8. Subjects are pregnant, attempting to become pregnant or breastfeeding;
• •9. Subjects who are currently smoking (including vaping, hookah and e-cigarette) or have smoking history within 1 year of study (defined as more than 1 pk/yr in the past year) or have a greater than equal to a 5 pack year smoking history;
• •10. Subjects living with a smoker who smokes inside the house;
• •11. Subjects who are current drinking or have frequent alcohol use (defined as at least 1 time per week) in the past 6 months;