Anti-aging Efficacy of Food Supplement and Cosmetic Routine

Exclusion Criteria

• •Female subjects: Pregnancy or lactation
• •Drug addicts, alcoholics
• •AIDS, HIV-positive or infectious hepatitis
• •Conditions which exclude a participation or might influence the test reaction/evaluation
• •Participation or being in the waiting period after participation in cosmetic and/or pharmaceutical studies pertaining to the test area
• •Active skin disease at the test area
• •Documented allergies to face/eye care products and food supplements or their ingredients
• •Intake of dietary supplements within the last 3 months before the start of the study
• •Diabetes mellitus
• •Cancer not being diagnosed as cured and requiring chemotherapy, irradiation and/or hormonal treatment within the last 2 years
• •One of the following illnesses with reduced physical capability/fitness: asthma (symptom-free allergic asthma is not an exclusion criterion), hypertension (if not adjusted with medication), cardiovascular diseases
• •Epilepsy
• •Wounds, moles, tattoos, scars, irritated skin, excessive hair growth, freckles, etc. at the test area that could influence the investigation
• •Regular use of tanning beds
• •Any topical medication at the test area within the last 3 days prior to the start of the study
• •Systemic therapy with immuno-suppressive drugs (e.g. corticosteroids) and/or antihistamines (e.g. antiallergics) and/or within the last 7 days prior to the start of the study
• •Therapy with antibiotics within the last 2 weeks prior to the start of the study
• •Past cosmetic surgery procedure in the test area (e.g. laser, facelift)
• •Cosmetic surgery procedure in the test area, e.g. IPL (Intensed Pulsed Light), botox, chemical peel, dermabrasion within the last 2 years prior to the start of the study and/or throughout the entire course of the study
• •Medical treatment for wrinkle reduction (e.g. peeling with vitamin A or fruit acids) on the face within the last 2 weeks prior to the start of the study
• •For biopsy subpanel:
• •Regular medication with anti-coagulating drugs like Aspirin®, Macumar®, etc. (e.g. for thrombosis prophylaxis) within up to 15 days prior to the taking of the biopsies
• •History of complications at wound healing (e.g. keloids, hypertrophic scars or contracture scar)
• •Known intolerance to local anaesthetics
• •Known Sensitivity to any dressing systems