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Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells | Clinical Trials | Clareo Health

RECRUITINGNA

Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells

NCT06930976•Vanderbilt University Medical Center

Summary

The purpose of this study is to understand how cells of the immune system use the common sugar glucose to fuel energy production and as a building block within the cell. Investigators will intravenously infuse a non-radioactive glucose tracer into participants over a few hours and collect immune cells from the blood to track uptake and usage of this glucose within these immune cells.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Adults aged 18 or older

Exclusion Criteria

•Pregnant
•Prisoner or in police custody
•Uncontrolled hyperglycemia/diabetes
•Current participation in another study where the total volume of blood drawn, when added to this study blood draw volume, exceeds 500cc in an 8 week period
•Any medical issue or pharmacologic exposure which, in the opinion of the study investigator, that might interfere with the study objectives
•Any reason which, in the opinion of the study investigator, adds additional risk to the participant

Locations (1)

Vanderbilt University Medical Center

Nashville, Tennessee, United States

Key Dates

Start Date

October 1, 2025

Primary Completion Date

June 30, 2027

Completion Date

June 30, 2027

Last Updated

November 4, 2025

Enrollment

ESTIMATED participants

Conditions

GlucoseMetabolismIsotope LabelingImmune System and Related Disorders

Interventions

13C6-Glucose

DRUG

Contacts

Matthew T Stier, M.D., Ph.D.

CONTACT

615-875-4978 matthew.stier@vumc.org

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 4, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

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Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells

Inclusion Criteria

Exclusion Criteria

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