Research on the Safety and Efficacy of Intraoperative Radiation Therapy in Malignant Cerebral Tumor

Inclusion Criteria

• •18-75 years old, non-pregnant or lactating women
• •KPS ≥60
• •MRI and CT of the brain with contrast should be considered for diagnosis of high-grade glioma or other malignant brain tumors
• •No other underlying diseases that affect survival time, follow-up or quality of life, and no other serious organic lesions
• •Not receive radiotherapy, chemotherapy and other treatment methods for intracranial lesions in the past;
• •Tumor located supratentorium, and the position should ensure that the tumor resection volume is more than 90%;
• •The required dose of standard radiotherapy exceeds normal tissue tolerance
• •No related contraindications such as intraoperative radiotherapy and craniotomy.