The Impact of Gestational Diabetes Mellitus on Cerebral Blood Flow and Cerebrovascular Function After Pregnancy

Exclusion Criteria

• •Skin diseases
• •Current tobacco use
• •Diagnosed or suspected hepatic or metabolic disease including diabetes
• •Diagnosed with depression or other mood-related disorders, asthma, chronic obstructive pulmonary disease, cystic fibrosis, or pulmonary fibrosis
• •Use of prescribed NSAIDs, statins or other cholesterol-lowering medication, antihypertensive medication, carbonic anhydrase inhibitors, corticosteroids, thyroid medications, antidepressants or mood stabilizers, diuretics, phenothiazines, or benzodiazepines
• •History of preeclampsia or gestational hypertension,
• •History or family history of panic disorder,
• •Currently pregnant
• •Body mass index \<18.5 kg/m2,
• •Allergy to materials used during the experiment (e.g. latex), known allergies to study drugs.
• •History of heavy alcohol use/binge drinking,
• •Have planned procedures with radiological contrast,
• •Have a major dental procedure/surgery coming up, such as a dental extraction
• •Anatomy of the middle cerebral artery or internal carotid artery that prevents adequate ultrasonography and/or and data collection