M-Gard Particulate EW Efficacy Study on Seasonal Allergic Rhinitis

Exclusion Criteria

• •Serious illness e.g., liver disease, kidney disease, heart disease, mood disorders, neurological disorders such as multiple sclerosis.
• •Unstable illness e.g., diabetes and thyroid gland dysfunction.
• •Current malignancy (excluding Basal Cell Carcinoma) or chemotherapy or radiotherapy treatment for malignancy within the previous 2 years.
• •Individuals with symptomatic perennial allergic rhinitis, non-allergic rhinitis, chronic respiratory conditions (e.g., asthma, chronic obstructive pulmonary disease).
• •Participants with cognitive damage.
• •Acute illness experienced in the past 1 month.
• •Active smokers and/or nicotine or drug abuse.
• •Allergic to any of the ingredients in the active or placebo formula.
• •Chronic past and/or current alcohol use (\>21 alcoholic drinks per week)
• •Attempting to conceive, pregnant or lactating women
• •Use of medications that would affect the immune and/or the inflammatory response e.g. immunotherapy, antihistamines (daily use), corticosteroids, mast cell stabilizers, leukotriene modifiers, and decongestants.
• •Currently taking Coumadin (Warfarin), Heparin, Dalteparin, Enoxaparin or other anticoagulation therapy including low dose aspirin; tricyclic antidepressants; Clonidine and other central acting alpha-2-agonists.
• •Participants who are currently participating in any other clinical trial or who have participated in any other clinical trial during the past 1 month.
• •Any condition which in the opinion of the investigator makes the participant unsuitable for inclusion.