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Effect of L-carnitine Supplementation on Phenylalanine and Brain-derived Neurotrophic Factor Levels in Infants and Children With Phenylketonuria Two Phases Study 1- Cross Sectional Comparative Study ( PKU Versus Non PKU Infants and Children). 2- Open Label Randomized Controlled Clinical Trial for PKU Patients Only. 1/ Intervention Group: 44 Patients Will Treated With L-carnitine at a Dose of 100 mg/kg/Dose for One Year Beside Their Treatment. 2/ Control PKU Group: 44 Patients Will Not Receive L-carnitine Supplementation Beside Their Treatment 3/ Control Healthy Group Same Age and Sex
Conditions
Interventions
L-carnitine
Locations
1
Egypt
Mansoura University
Al Mansurah, Egypt
Start Date
February 1, 2025
Primary Completion Date
March 1, 2026
Completion Date
August 1, 2026
Last Updated
April 4, 2025
NCT06628128
NCT05579548
NCT06560736
NCT06332807
NCT06780332
NCT04348708
Lead Sponsor
Mansoura University
Data Source & Attribution
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