Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Male or female, between 18 and 65 years old;
Diagnosed with SLE according to 2019 EULAR/ACR SLE classifications;
Positivity for ANA (titer≥1:80), and/or anti-dsDNA, and/or anti-Smith antibody at screening;
SLEDAI-2K≥8 points (with a clinical SLEDAI-2K≥6 points) ;
Patients who have used stable standard treatment regimen for at least 6 months in their medical history before screening, and their condition is still active for at least 2 months before screening.
Good organ functions;
Voluntary participates this trial and can comprehend and sign ICF.
You may not be if
Had or has active malignancy;
Had been subjected to treatment by CD19 targeted therapy or CAR-T therapy or any gene therapy;
Combined with other autoimmune disease that needs treatment;
Pregnant or lactating women;
Has other factors that deemed not suitable by investigator.
