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Optimizing Health Related Quality of Life Measurement in Adolescent and Young Adult Oncology: A Promising Solution (PROMIS AYA) - Aim 2
This study evaluates how adolescent and young adults with cancer in the U.S. and their loved ones respond to questions that will later be used with people who may have cancer and other chronic health conditions
PRIMARY OBJECTIVES: * To refine patient-reported outcome assessment tools of body image, fertility, and financial burden for PROMIS and evaluate assumptions for IRT consistent with PROMIS Scientific Standards (e.g., unidimensionality, local independence). * To examine item-level properties to support computer adaptive testing and evaluate possible differential item functioning (DIF). Secondary Objective * To create short forms and examine convergent validity of the new body image, fertility, and financial burden short forms and item banks with corresponding legacy measures of those constructs. OUTLINE: This is an observational study. Participants complete surveys on study.
Age
15 - No limit years
Sex
ALL
Healthy Volunteers
Yes
Wake Forest Baptist Comprehensive Cancer Center
Winston-Salem, North Carolina, United States
Start Date
April 1, 2026
Primary Completion Date
January 1, 2028
Completion Date
January 1, 2028
Last Updated
February 24, 2026
3,000
ESTIMATED participants
Surveys/Questionnaires
OTHER
Lead Sponsor
Wake Forest University Health Sciences
Collaborators
NCT05372640
NCT05039801
Data Source & Attribution
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