Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Merck Sharp & Dohme LLC
Age
18–55
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Is a healthy, adult, male or female of non-childbearing potential only, 18-55 years of age, inclusive
Is a continuous non-smoker who has not used nicotine- and tobacco-containing products for at least 3 months prior
You may not be if
Has a history or presence of:
* Seizures (except for febrile seizure), or is at an increased risk for seizures
* Family history of severe dermatologic reactions including toxic epidermal necrolysis and Stevens-Johnson syndrome
* Clinically meaningful hematologic diseases, bone marrow disorders, or hematologic adverse reactions to other medications
* Depression, unusual changes in mood or behavior or suicidal thoughts or behavior
* Hypersensitivity reaction to anticonvulsant therapy (including phenytoin, primidone, and phenobarbital)
* Clinically significant eye disease
* Cardiac conduction disturbance, including second-and third-degree atrioventricular heart block
Shown to carry or be positive for HLA-A\*11:01, HLA-A\*31:01, HLA-B\*15:02, HLA-B\*15:08, HLA-B\*15:11, HLA-B\*15:21, HLA-B\*15:30, or HLA-B\*15:31 alleles.
