South Korean Study to Prevent Frailty and Aging-related Diseases Through Lifestyle Intervention

Exclusion Criteria

• •Major psychiatric illness such as major depressive disorders
• •Dementia
• •Other neurodegenerative disease (e.g., Parkinson's disease)
• •Malignancy within five years
• •Cardiac stent or revascularization within one year
• •Serious or unstable symptomatic cardiovascular disease
• •Other serious or unstable medical disease such as acute or severe asthma, active gastric ulcer, severe liver disease, or severe renal disease
• •Severe loss of vision, hearing, or communicative disability
• •Significant laboratory abnormality that may result in cognitive impairment
• •Any conditions preventing cooperation as judged by the study physician
• •Unable to participate in exercise program safely
• •Coincident participation in any other intervention trial