Clinically confirmed MSA and clinically probable MSA according to the 2022 MDS MSA diagnostic criteria;
all patients had been ruled out of polyQ disease by genetic testing;
Voluntarily participate in this study and sign the informed consent form.
You may not be if
pregnancy or breastfeeding;
contraindications to MRI examination or inability to cooperate in completing neuroimaging examination;
previous history of other neurological disorders or presence of other organic intracranial lesions on neuroimaging that cannot be interpreted by MSA, such as epilepsy, trauma, tumors, or high-grade cerebral white matter degeneration (Fazekas grade 2 and above);
History of alcohol or drug abuse
Clareo Health | TSPO PET in the Evaluation of Neuroinflammation in Patients with Multiple System Atrophy