Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Illinois at Chicago
This is an exploratory, randomized, crossover-controlled feeding study of a 4-week Mediterranean Diet or usual diet control among 24 adults with sickle cell disease and chronic pain (30 will be recruited, with an estimated 24 participants completing the study).
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Sickle Cell Disease Diagnosis
Chronic non-vaso-occlusive pain experienced on average ≥ 3 days per week for \> 6 months (based on a response of "Most days," "Every day," or "Some days" and not "Never" to the question "In the past 6 months, how often have you had pain?")
Ability to speak, read, write, and understand English
A Mediterranean Eating Pattern for Americans (MEPA-III) score \<13, indicating that they do not follow a Mediterranean diet.
You may not be if
Having taken systemic antimicrobials (to treat an infection in the previous 4 weeks)
History of colon cancer or inflammatory bowel disease (given potential untoward effects on the gut microbiome)
History of Clostridium difficile infection in the preceding 12 weeks;
Unable to agree to maintain physical activity at the current level for the duration of the study
Currently following a Mediterranean diet, vegan diet, or dietary restrictions (e.g., religious, food intolerance/allergy) that preclude adoption of a Mediterranean diet
Lack of access to a space to safely store and reheat food items
Living in a facility that provides meals.
Pregnancy or breastfeeding
More than 7 in-patient hospital stays in the last year
